Anti-diabetic activity of Ginger tuber proteins : In vitro studies

Authors

  • Chikkanna Dodda Huchaiah Dept. of Biochemistry, Adichunchanagiri Institute of Medical Sciences, B.G. Nagara. Author
  • Dinesha Ramadas AIMS- Central Research Laboratory, Adichunchanagiri Biotechnology & Cancer Research Institute, B.G. Nagara-571 448, Karnataka, India. Author
  • Subhas Chandrappa Mundasada Dept. of Biochemistry, Basaveshwara Medical College Chitradurga, Karnataka, India. Author
  • Santosh Kumar Nune Dept. of Biochemistry, Shridevi Institute of Medical Sciences and Research Hospital, Tumkur-572106, Karnataka, India. Author
  • Shwetha Kadalu Lingaraju AIMS- Central Research Laboratory, Adichunchanagiri Biotechnology & Cancer Research Institute, B.G. Nagara-571 448, Karnataka, India. Author
  • Ranjitha Puttaswamygowda AIMS- Central Research Laboratory, Adichunchanagiri Biotechnology & Cancer Research Institute, B.G. Nagara-571 448, Karnataka, India. Author

DOI:

https://doi.org/10.5530/aq0z2z63

Keywords:

Anti-diabetic, antioxidant, Ginger tuber, proteins, phytochemicals

Abstract

The study was done to investigate the in vitro antidiabetic activity of proteins from Ginger tuber. Phytochemicals of Ginger tuber proteins was analyzed by using standard methods. In vitro antioxidant studies were carried out for the Ginger tuber proteins using DPPH model, In vitro anti-diabetic studies was done by alpha amylase enzyme, alpha glucosidases enzyme inhibition studies and Glucose uptake in Yeast cells studies. The phytochemical screening of Ginger tuber proteins showed that the extract contains more proteins and contains negligible amount of other phytochemicals. The in vitro antidiabetic potential of extract was confirmed through alpha amylase enzyme, alpha glucosidases enzyme inhibition studies and Glucose uptake in Yeast cells studies. The results of the present study concluded that the Ginger tuber proteins possess significant antioxidant and antidiabetic activity. The potential pharmacological activity of Ginger tuber proteins might be due to the presence of proteins.

 

 

 

 

Author Biographies

  • Chikkanna Dodda Huchaiah, Dept. of Biochemistry, Adichunchanagiri Institute of Medical Sciences, B.G. Nagara.

     

     
  • Dinesha Ramadas, AIMS- Central Research Laboratory, Adichunchanagiri Biotechnology & Cancer Research Institute, B.G. Nagara-571 448, Karnataka, India.

     

       
  • Subhas Chandrappa Mundasada, Dept. of Biochemistry, Basaveshwara Medical College Chitradurga, Karnataka, India.

     

     
  • Santosh Kumar Nune, Dept. of Biochemistry, Shridevi Institute of Medical Sciences and Research Hospital, Tumkur-572106, Karnataka, India.

     

     
  • Shwetha Kadalu Lingaraju, AIMS- Central Research Laboratory, Adichunchanagiri Biotechnology & Cancer Research Institute, B.G. Nagara-571 448, Karnataka, India.

     

     
  • Ranjitha Puttaswamygowda, AIMS- Central Research Laboratory, Adichunchanagiri Biotechnology & Cancer Research Institute, B.G. Nagara-571 448, Karnataka, India.

     

     

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Published

2016-06-30

Issue

Section

Articles

How to Cite

Anti-diabetic activity of Ginger tuber proteins : In vitro studies. (2016). Asian Journal of Pharmaceutical and Health Sciences, 6(2), 1472-1476. https://doi.org/10.5530/aq0z2z63