Placental Mesenchymal Dysplasia - A Differential Diagnosis of Molar Pregnancy: A Case Report

Asian Journal of Pharmaceutical and Health Sciences,2015,5,4,1368-1371.
Published:December 2015
Type:Case Report
Author(s) affiliations:

Rama Saha1, Aruna Bhattacharya2, Joydip Deb3

1Associate Professor, Department of Biochemistry, IPGME and Kolkata, West Bengal, India. 

2Assistant Professor, Department of Biochemistry, B.S. Medical College and Hospital, Bankura, West Bengal, India.

3Department of Chest Medicine, B.S. Medical College and Hospital, Bankura, West Bengal, India.


Placental mesenchymal dysplasia (PMD) is a rare placental abnormality characterised by placentomegaly and grape-like vesicles resembling partial mole by ultrasonography, but in contrast to partial mole, can co-exist with a viable fetus. Although the karyotype is normal, the fetus is at increased risk for intrauterine growth restriction, intrauterine fetal demise or perinatal death and Beckwith-Wiedemann syndrome. Prenatal diagnosis is difficult and the final diagnosis is usually achieved by postpartum histological examination of the placenta. We present a case of a stillborn who had a placenta praevia radiologically and was seen to have mesenchymal dysplasia on histological examination.

Figure 2