Clomipramine Induced Torticollis: A Case Report

Torticollis caused by clomipramine: a case report Drug-induced torticollis is a movement disorder that occurs most often with neuroleptics, though there are many drugs in its etiology. The exact mechanism of antidepressant-associated extrapyramidal side effects (EPS) is not known. However, hypotheses including inhibition of dopaminergic function in the nigrostriatal pathway, impaired balance between dopaminergic, serotonergic, noradrenergic or cholinergic activity, and serotonergic inhibition of dopaminergic functions in the striatum leading to extrapyramidal side effects have been suggested. The number of cases with torticollis during clomipramine use is low. We wish to draw attention to this rare side effect of clomipramine and to contribute to the literature by presenting a case of torticollis on the 5th day of clomipramine treatment in a 22-year-old male 1 patient¹.