Unraveling the Uncommon: A Case Report of Cholinergic Urticaria Associated with Pityriasis Versicolor in a Postmenopausal Woman

Pityriasis versicolor, characterized by pigmentary changes due to Malassezia yeast colonization, is a common cutaneous fungal infection. However, its association with cholinergic urticaria is rare. We present a case of a 52-year-old postmenopausal woman with persistent sore throat and hypopigmented, scaly lesions on her arms and thighs, accompanied by severe Pruritis. Concerns regarding hormonal changes post-menopause prompted consultation with an allergist. Referral to a dermatologist revealed cholinergic urticaria associated with pityriasis versicolor, a rare fungal infection. Treatment with luliconazole, fluconazole, and cyproheptadine led to a significant improvement in her symptoms. This case highlights the importance of considering uncommon presentations and interdisciplinary collaboration in managing complex dermatological conditions.Pityriasis versicolor, characterized by pigmentary changes due to Malassezia yeast colonization, is a common cutaneous fungal infection. However, its association with cholinergic urticaria is rare. We present a case of a 52-year-old postmenopausal woman with persistent sore throat and hypopigmented, scaly lesions on her arms and thighs, accompanied by severe Pruritis. Concerns regarding hormonal changes post-menopause prompted consultation with an allergist. Referral to a dermatologist revealed cholinergic urticaria associated with pityriasis versicolor, a rare fungal infection. Treatment with luliconazole, fluconazole, and cyproheptadine led to a significant improvement in her symptoms. This case highlights the importance of considering uncommon presentations and interdisciplinary collaboration in managing complex dermatological conditions.