Anti-diabetic Activity of Ginger Tuber Proteins: in vitro Studies

Asian Journal of Pharmaceutical and Health Sciences,2016,6,2,1472-1476.
Published:June 2016
Type:Research Article
Authors:
Author(s) affiliations:

Chikkanna Dodda Huchaiah1, Dinesha Ramadas2*, Subhas Chandrappa Mundasada3, Santosh Kumar Nune4, Shwetha Kadalu Lingaraju2 and Ranjitha Puttaswamygowda2

1Department of Biochemistry, Adichunchanagiri Institute of Medical Sciences, B.G. Nagara, Karnataka, India. 

2AIMS- Central Research Laboratory, Adichunchanagiri Biotechnology and Cancer Research Institute, B.G. Nagara-571 448, Karnataka, India.

3Department of Biochemistry, Basaveshwara Medical College Chitradurga, Karnataka, India.

4Department of Biochemistry, Shridevi Institute of Medical Sciences and Research Hospital, Tumkur-572106, Karnataka, India.

Abstract:

The study was done to investigate the in vitro antidiabetic activity of proteins from Ginger tuber. Phytochemicals of Ginger tuber proteins was analyzed by using standard methods. In vitro antioxidant studies were carried out for the Ginger tuber proteins using DPPH model, In vitro anti-diabetic studies was done by alpha amylase enzyme, alpha glucosidases enzyme inhibition studies and Glucose uptake in Yeast cells studies. The phytochemical screening of Ginger tuber proteins showed that the extract contains more proteins and contains negligible amount of other phytochemicals. The in vitro antidiabetic potential of extract was confirmed through alpha amylase enzyme, alpha glucosidases enzyme inhibition studies and Glucose uptake in Yeast cells studies. The results of the present study concluded that the Ginger tuber proteins possess significant antioxidant and antidiabetic activity. The potential pharmacological activity of Ginger tuber proteins might be due to the presence of proteins

DPPH radical scavenging activity of Ginger proteins