The most common sites of prostate cancer metastasis include the bone, lung and liver. Brain metastasis is very rare. Metastasis to multiple sites including the less frequent sites is even rare occurrence. On the other hand, the diagnosis of metastatic prostate carcinoma to the brain has rarely been published and mainly reported as autopsy series. Brain metastasis from prostate carcinoma represent often a late event when the disease has already metastasizes widespread to other organs. There is advancement in the management by understanding its natural course and development of newer agent in the form of chemotherapy, hormonal therapy as well as targeted therapy along with other established treatment modalities. The prostate carcinoma patient with multiple site metastasis show dismal survival in-spite of advancement in screening, diagnosis and treatment modalities. Here we are reporting a case of Ca Prostate with multiple metastases who survived 3 years without taking any treatment.
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