Pregnancy requires specialized care generally agreed to preventive activity. Safe delivery [motherhood] is defined as ensuring essential maternal and newborn care during pregnancy and child birth. The aim of the study was to assess the level of knowledge regarding safe delivery and to associate the level of knowledge regarding safe delivery among primigravida mothers with their demographics variables. Quantitative approach and Non Experimental descriptive research design was used. The tool used for the study comprises of 2 sections. Section A Demographic Data (which includes age, gender, educational status, occupation, religion, age at married, income, type of family, weeks of gestation, registration of pregnancy) and section B- a structured questionnaire developed by the investigator which includes 30 questions to assess the knowledge on safe delivery. 100 primigravida mothers who fulfilled the inclusion criteria were selected as samples using non-probability convenient sampling technique. The study was conducted at SRM rural health Center at mamandur village, Kancheepuram district. The data was analyzed and interpreted based on the objectives using descriptive and inferential Statistics. The Study concluded that among 100 primigravida mothers, 0 (0%) of them have inadequate knowledge, 54 (54%) antenatal mothers have moderately adequate knowledge regarding safe delivery; 46 (46%) have adequate knowledge. There is a significant association on level of knowledge on safe delivery among primigravida mothers and with their selected demographic variables such as age at marriage and weeks of gestation. The safe motherhood initiative placed special emphasis on the need for better and more widely available maternal health services, the extension of family planning education and services and effective measures which is influenced by women's health and nutritional status, reproductive and health behaviours and access to family planning and maternal care services.