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Human Cytomegalovirus IgM Antibodies Seropositivity Among Pregnant Women in Ante-natal Clinics in Birnin-Kebbi, Kebbi State, Nigeria

Asian Journal of Pharmaceutical and Health Sciences,2016,6,3,1509-1513.
Published:September 2016
Type:Research Article
Authors:
Author(s) affiliations:

Chilaka Chidinma Glory1*, Manga Shuaibu Bala2, Yakubu SE3, Ukatu Victoria Ebere4, Fardami Aminu1, Rupashree Singh5

1Mayo Foundation Clinic and Maternity, P.O. Box- 385, Birnin Kebbi, Kebbi State, Nigeria.

2Department of Microbiology, Usmanu Danfodiyo University, PMB 2346, Sokoto, Nigeria.

3Department of Microbiology, Ahmadu Bello University, Zaria, PMB 1045, Kaduna, Nigeria.

4Department of Biological Sciences, Kebbi State University of Science and Technology, Aliero, PMB:1144, Kebbi State, Nigeria.

5Department of Biological Sciences, Sokoto State University, PMB: 2134, Sokoto State, Nigeria.

Abstract:

Infection with Cytomegalovirus (CMV), especially in pregnancy, may cause pregnancy complications such as congenital infection, non-hereditary deafness, intrauterine growth restriction and other health defects. The objective of this study was to evaluate the prevalence of CMV IgM antibodies in pregnant women attending antenatal clinics at General Hospital, Zauro/Ambursa and Mayo Foundation Clinic and Maternity, Birnin-Kebbi. Serum samples were collected from 92 pregnant women. CMV IgM antibodies were detected using an enzymelinked immunosorbent assay method for IgM. Of the 92 pregnant women tested, CMV IgM antibody was found in 1(1.1%) of the women while 91(98.9%) did not have the CMV IgM antibodies. The diagnosed CMV IgM antibody seropositive pregnant women was educated, civil servants, residing in the urban areas and in her third trimester in first pregnancy. Although, a low proportion of pregnant women is exposed to CMV current infection, it is recommended that there should be voluntary screening of all pregnant women, as part of their antenatal care, so that seropositive women with primary infection could be offered the opportunity for prenatal screening and be informed of intervention options.

CMV IgM antibodies in the pregnant women involved in the study according to their age groups