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Mature Cystic Teratoma of Ovary Transforming to Squamous Cell Carcinoma - A Case Report

Asian Journal of Pharmaceutical and Health Sciences,2015,5,3,1314-1316.
Published:August 2015
Type:Case Report
Authors:
Author(s) affiliations:

Rama Saha1, Aruna Bhattacharya2,*, Ddahra Patricia Beso3, Ankita Sen4, Joydip5

1Associate Professor, Department of Pathology, Institute of Postgraduate Medical Education and Research, Kolkata-20, West Bengal, India.

2Assistant Professor, Department of Biochemistry, B.S Medical College, Bankura, West Bengal, India.

3Department of Pathology, Institute of Postgraduate Medical Education and Research, Kolkata-20, West Bengal, India.

4Fellow, Lab Haematology, Tata Medical Centre, Kolkata, West Bengal, India.

5Head, Department of Chest Medicine, Bankura Sammilani Medical College and Hospital, Bankura, West Bengal, India.

Abstract:

Mature cystic teratoma (MCT) accounts for 30-45% of all ovarian tumors. Malignant transformation of these tumors is a rare event ,which develops only in 1 to 2% of the cases. But it must be highlighted that though it may be a rare occurrence, malignant transformation is associated with a poor prognosis. Of all transformations, squamous cell carcinoma (SCC) is the most common histological type accounting for about 75% of all malignant transformations. We hereby report a case of a 49 year old female with mass in abdomen for 3 months associated with pain. Ultrasound studies suggested an ovarian tumor-solid cystic teratoma. Total abdomimal hysterectomy with bilateral salphingo oopherectomy was done. Moderately differentiated invasive squamous cell carcinoma arising in a background of mature cystic teratoma was diagnosed by histopathological studies.

Gross -dermoid cyst with thickened hard area