Students' feedback plays a vital role, as suggested by the literature review, in effectively reforming the learning and teaching methods in medical sciences. The present study has been conducted to obtain students' attitude (perception of) towards different teaching and learning methods of pharmacology. The sample consisted of second phase M.B.B.S (n=108) students. Students answered 80 items/questions designed according to Likert's five point (in agreement with items) scale. These items/questions assessed students' attitude (perception of) towards various teaching and learning methods of pharmacology like theory class teaching, tutorial, integrated teaching and clinical/bedside teaching in relation with different constituents of pharmacology subject like classification of drugs, pharmacological actions etc. Similarly students' attitude towards novel teaching methods like CAL, PBL, e-learning etc with regard to understanding, retention, learning clinical applications of pharmacology subject etc has been obtained. Results of the present study indicated the degree to which each teaching and learning method, existing as well as novel methods, helps in understanding different constituents of pharmacology subject as mentioned earlier. Present study indicated the merits and demerits of different teaching and learning methods used in pharmacology. This study will be helpful if any reformations/changes have to be brought into the teaching and learning methods of pharmacology. This study will also be helpful if some of the novel teaching and learning methods, as discussed, have to be introduced into the curriculum.