There will be concerns about whether Continuing Medical Education (CME) works or how we should present (technique of delivery) it. Literature survey indicates the strong need to evaluate the CMEs. Therefore in the present study two CME's have been evaluated. Two CMEs, one at regional (on Clinical Research, n=210) and another at national level (on Pharmacovigilance, n=230) were evaluated. Both were lecture based programmes. Pre and post tests were conducted by using validated M.C.Qs. Delegates evaluated each resource person by using a five point scale. Feedback regarding entire learning environment was taken. Statistical analysis (p<0.05, considered as significant) was done. Both CMEs were significantly effective in cognitive tests of knowledge. Both CMEs were informative and effective. Each resource person's lecture was effective (excellent to moderate). A collaborative approach was followed. In both the CMEs educators have done systematic research, derived practical and effective results that created or improved learning systems. The continual flow of ideas about the subjects was maintained in both the CMEs. Delegates' feedback indicated that learning environments of CMEs were favourable and delegates expressed what they need in future CMEs. Learner centred sessions will be stressed more in future CMEs.